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    Coadministration of other medicinal products known to prolong the QT interval and which are metabolised via the cytochrome P CYP 3A4 such as cisapride, astemizole, pimozide, quinidine and erythromycin are contraindicated in patients receiving fluconazole see sections 4. https://eqstl.com/fluconazole/fluconazole-150mg-1.

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    The QT prolongation caused by other medicinal products such as amiodarone may be amplified via the inhibition of cytochrome P CYP 3A4. Patients with impaired renal function will be at risk of overdose. Adrenal insufficiency Ketoconazole is known to cause adrenal insufficiency, and this could also although rarely seen be applicable to fluconazole.


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