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Accutane (isotretinoin) 5 mg, pde5 inhibitors such as relax smooth muscle and increase blood flow to the penis.

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Clinical data
PronunciationSee note at tretinoin
Trade namesAccutane (originator), subsequently many generics [1]
License dataUS   FDA: Isotretinoin
Pregnancy categoryAU: X (High risk) US: X (Contraindicated)
Routes of administrationBy mouth, topical
ATC codeD10AD04 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Protein binding99.9%
Elimination half-life10–20 hours
ExcretionRenal and fecal

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Accutane, 2 reviews:

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Dry eyes are very common during treatment and is caused by isotretinoin's apoptotic effect on the meibomian glands.

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