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Isotretinoin
Clinical data
PronunciationSee note at tretinoin
Trade namesAccutane (originator), subsequently many generics [1]
AHFS/Drugs.comMonograph
MedlinePlusa681043
License dataUS   FDA: Isotretinoin
Pregnancy categoryAU: X (High risk) US: X (Contraindicated)
Routes of administrationBy mouth, topical
ATC codeD10AD04 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityVariable
Protein binding99.9%
MetabolismHepatic
Elimination half-life10–20 hours
ExcretionRenal and fecal

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Generic brands are designed to be substitutes for more expensive brand-name goods. Your local postman either delivers the package or leaves a notice in case you are not at home. The contents of the pills are absolutely the same in our generic version as in the branded analogue. You and your You and your means the user of the website can contact Customer Service by email hello@doiydesign. If you still haven't received the package, please contact your post office, the package may be there.

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Dry eyes are very common during treatment and is caused by isotretinoin's apoptotic effect on the meibomian glands.


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