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    It is the therapeutically active S-enantiomer of citalopram. Overall, while most systematic reviews suggest that Lexapro is more effective than Celexa in the treatment of major depressive disorder, these reviews base this suggestion on data from trials that are riddled with limitations.

    Celexa may cause gastrointestinal upset, insomnia, drowsiness, dry mouth, ejaculation disorder, bleeding abnormalities, weight changes, increased urination, decreased sex drive, impotence, difficulty having an orgasm, dry or watery mouth and yawning; or cold symptoms such as sneezing, sore throat or a stuffy nose. Food and Drug Administration for anxiety treatment.

    Lexapro was developed and produced in Like right and left hands, enantiomers are mirror images of each other. Additionally, in the review by Cipriani et al.

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    Of the articles reporting either of these outcomes, some reported estimates predictions from logistic regression analyses by treatment group, while others reported crude i. Discussion This meta-analysis of all the publicly available data indicates that escitalopram has superior efficacy compared to citalopram in the treatment of MDD in a patient population citalopram vs lexapro both moderate and severe disorder.

    Escitalopram has been shown to be superior to paroxetine Boulenger et al.

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    As of current, it is unknown as to whether there are clinically-relevant differences in the efficacies of Celexa and Lexapro in the management of social anxiety disorder, however, there are stronger data supporting the use of Lexapro for this condition than there are supporting the use of Celexa. Lexapro is a more expensive option than the citalopram, the generic citalopram compared to lexapro of Celexa.

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    In the case of citalopram this difference was 1. In the first case, adjusted estimates were converted to number of patients that, for example, were in remission by multiplying the estimated predictions by the by-treatment FAS sample size.

    Uses and Efficacy Lexapro is approved to treat anxiety disorders, whereas Celexa is not. Efficacy and tolerability of escitalopram versus citalopram in major depressive disorder: The superior antidepressant efficacy of Lexapro relative to Celexa was evidenced by: Overall, the findings presented in this comprehensive systematic review by Cipriani et al.

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