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Sildenafil
Clinical data
Pronunciation/ s ɪ l ˈ d ɛ n ə f ɪ l / sil- DEN -ə-fil
Trade namesViagra, Revatio, others
AHFS/Drugs.comMonograph
MedlinePlusa699015
License dataEU  EMA:  by INN, US   FDA: Sildenafil
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationBy mouth (tablets), IV
ATC codeG04BE03 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability41% (mean) [1]
Protein binding~96%
MetabolismLiver: CYP3A4 (major route), CYP2C9 (minor route)
MetabolitesN -desmethylsildenafil (~50% potency for PDE 5 )
Elimination half-life3–4 hours
ExcretionFeces (~80%), urine (~13%) [2]

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Brand names Why is this medication prescribed? Went with the generic because of the incredibly high price of original brand. With one 20 mg dose all is well. Continue to take sildenafil even if you feel well.

Children should not usually take sildenafil, but in some cases, a doctor may decide that sildenafil Revatio is the best medication to treat a child's condition. The name Viagra is still a brand name which only Pfizer can use.

Little bit of nose stuffiness. If there is a downside, it's only that I can't always "finish" Not a concern for me.

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