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As further improvement of the acne can be observed up to 8 weeks after discontinuation of treatment, a further course of treatment should not be considered until at least this period has elapsed.
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You will receive no more than a day supply of Accutane at one time. Isotretinoin in the treatment of acne variants. When macrocomedones are not the cause of poor response, the dosage of isotretinoin should be carefully considered as some patients will suffer a deterioration in their acne at the start of a course of isotretinoin.
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