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Clinical data | |
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Pronunciation | / s ɪ l ˈ d ɛ n ə f ɪ l / sil- DEN -ə-fil |
Trade names | Viagra, Revatio, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a699015 |
License data | EU EMA: by INN, US FDA: Sildenafil |
Pregnancy category | AU: B1 US: B (No risk in non-human studies) |
Routes of administration | By mouth (tablets), IV |
ATC code | G04BE03 ( WHO ) |
Legal status | |
Legal status | AU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only) |
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Bioavailability | 41% (mean) [1] |
Protein binding | ~96% |
Metabolism | Liver: CYP3A4 (major route), CYP2C9 (minor route) |
Metabolites | N -desmethylsildenafil (~50% potency for PDE 5 ) |
Elimination half-life | 3–4 hours |
Excretion | Feces (~80%), urine (~13%) [2] |
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The pharmaceutical company Teva will manufacture generic Viagra. One of the new generics is made by Teva Pharmaceuticals, and the other by Greenstone, a subsidiary of Pfizer, the company that manufactures Viagra.
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Both doctors said this has led many men in the United States to buy erectile dysfunction drugs online or in Canada. Impotence can be the first sign of heart disease, particularly in younger men, he said.
Both doctors said this has led many men in the United States to buy erectile dysfunction drugs online or in Canada. The most popular generic drug for erectile dysfunction treatment is generic Viagra. The dosage of the new medication will correspond the original Viagra dosages or diabetes management. Only recently was the production of generic Viagra approved in the United States of America.
And more generic versions are expected next year, which could drive prices even lower. The company estimates that 80 percent to 85 percent of retail pharmacies in the United States participate in this plan.
Viagra came on the market in as the first drug to treat impotence. They can include headache, flushing of the face, nausea, lightheadedness, and a temporary bluish-tint to vision, Bromberg said.
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Like most medications | The manufacturing company plans to release pills with 25 | Viagra came on the market in as the first drug to treat impotence | The company estimates that 80 percent to 85 percent of retail pharmacies in the United States participate in this plan | |||
Another program is for those with insurance | Viagra came on the market in as the first drug to treat impotence | One of the new generics is made by Teva Pharmaceuticals | Pfizer |
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For men who pay cash and have a valid prescription, the company is offering home delivery Pfizer Direct of brand-name Viagra for about 50 percent off list price. Many patients have been unable to obtain the medication since insurance companies don't pay for it and out-of-pocket costs are astronomical," said Dr. Pfizer cannot estimate the cost per pill because different pharmacies charge different prices.
In the Chinese market, Viagra, sold under sources Chinese name of Wan Ai Ke, is being produced in a joint venture factory between Pfizer pharmaceutical and Dalian pharmaceutical in the northeastern Chinese city of Dalian.
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